CJC 1295 No DAC

CJC-1295 No DAC (Mod GRF 1-29)

CJC-1295 No DAC is a synthetic peptide analog. Specifically, it mimics Growth Hormone-Releasing Hormone (GHRH). However, it lacks the “DAC” (Drug Affinity Complex) modification. Therefore, it has a short half-life of about 30 minutes. We offer a high-purity 5mg vial. Currently, researchers prefer this version for “pulsatile” studies. So, it mimics the body’s natural rhythm. Thus, it avoids the side effects of constant stimulation.

How It Works

This peptide works by amplifying the natural signal. First, it binds to the GHRH receptor on the pituitary gland. Then, it signals the gland to produce more growth hormone. This means it increases the “volume” of the release. Unlike the DAC version, CJC-1295 No DAC allows the levels to drop back to baseline.

Consequently, this prevents “GH bleed.” GH bleed is when hormone levels stay high forever, which desensitizes the body. As a result, this specific peptide maintains pituitary sensitivity over long-term studies.

Lab Uses

Frequently, labs use CJC-1295 No DAC. Mainly, they use it for endocrine rhythm tracking. This helps map how the pituitary responds to short windows of stimulation. Next, researchers check for sleep quality. Specifically, they look at how GH pulses correlate with slow-wave sleep.

Moreover, it pairs perfectly with pulse initiators. Labs often stack it with Ipamorelin. See also: Synergistic Pairing: Ipamorelin for Clean Pulses

Ideally, this creates the perfect spike. While Ipamorelin starts the engine, CJC-1295 hits the gas. Finally, this provides a massive, yet natural, release of growth hormone.